The QSAR Application Toolbox was developed under the aegis of OECD to facilitate the use of the category approach and QSAR methods to fill data gaps in classification and labeling. Use of the Toolbox will save resources, reduce the need for animal testing, and greatly accelerate the hazard assessment process.
The Toolbox provides the ability to:
Make estimates of the relevant endpoints for single chemicals, linked to the CAS number or the chemical structure. Obtain summary information on the validation processes and results of the model so that the user can decide for which regulatory purpose the estimate can be used.
Obtain a list of analogues for a chemical, together with their experimental, or estimated environmental, toxic or health effects.
Obtain estimates for metabolite activation/detoxification information for the chemical.
Interface with IUCLID 5 with ability for automated submission of estimated values for registration purposes
Features of QSAR Toolbox 3.3:
Updated versions of six databases including REACH registration data from the REACH dissemination website;
IUCLID 5.5 compatibility;
Updated auto oxidation and rat liver metabolism simulators;
Updated versions of 12 profilers for grouping chemicals;
Enhanced user interface and other minor functionality improvements.
WHO SHOULD TAKE THIS OFFICIAL TRAINING?
QSAR Toolbox training is offered at two levels: Basic and Advanced. The Basic Training Course, which requires some knowledge of chemical structure, provides an overview of the Toolbox databases, modeling system, and use of QSAR methods for managing data and modeling, plus a hands-on introduction to filling data gaps for hazard assessment. The Advanced Training Course, for which the Basic Training Course is a prerequisite, is intended to provide the capability to make advanced hazard assessments for a wide variety of chemicals, along with documentation of the process in a form suitable for submission to regulatory agencies. Practicum training is offered for those who have completed the Basic and Advanced Training courses and wish to have additional practical work in applying the acquired skills to specific chemicals.
The Training Courses are designed for those charged with developing safety assessments for chemical manufacturers and distributors as well as for those charged with evaluating submitted assessments for new chemicals or those already in use in commerce. Those interested in or conducting research on QSAR tools and database development would also find the training useful.
FEES AND REQUIREMENTS
Course registration fee for each course is €1815 (includes 21% VAT) for industry trainees and €1210 (includes 21% VAT) for government and university trainees. Registration fee for Practicum is €907.50 (includes 21% VAT) for industry trainees and €605 (includes 21% VAT) for government and university trainees. This includes installation of the OECD Toolbox on each trainee’s laptop computer, all course materials, lunches, coffee breaks, and a Course Certificate. Language of the course is English. Trainees must provide their own laptop computers. Please visit the website above to register.